Importance of sites of tracer administration and sampling in turnover studies

Conference · Fri Jan 01 00:00:00 EST 1982 · Fed. Proc.; (United States)

OSTI ID:5655726

Katz, J

Our recent studies with tritium and /sup 14/C-labeled lactate and alanine in starved rats revealed that the sites of tracer administration and sampling have a profound effect on the kinetics of the specific activity curves and the calculation of metabolic parameters. The importance of the sites of tracer administration and sampling for the experimental design and interpretation of tracer data in vivo is discussed.

• Research Organization: Cedars - Sinai Medical Center, Los Angeles, CA
• OSTI ID: 5655726
• Journal Information: Fed. Proc.; (United States), Vol. 41:1; Conference: 64th Annual Meeting of the Federation of American Societies for Experimental Biology, Anaheim, CA, USA, 15 Apr 1980
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
ALANINES
METABOLISM
LACTATES
TRACER TECHNIQUES
BIOCHEMICAL REACTION KINETICS
CARBON 14 COMPOUNDS
IN VIVO
LABELLED COMPOUNDS
RATS
TRITIUM COMPOUNDS
AMINO ACIDS
ANIMALS
CARBOXYLIC ACID SALTS
CARBOXYLIC ACIDS
ISOTOPE APPLICATIONS
KINETICS
MAMMALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
REACTION KINETICS
RODENTS
VERTEBRATES
550501* - Metabolism- Tracer Techniques