Radiotherapy of prostatic carcinoma: long- or short-term efficacy (Stanford University experience)
Results of a study that began at Stanford in 1956 demonstrate that long-term, disease-free survival can be achieved following appropriate irradiation in patients with prostatic carcinoma. However, the investigation has also uncovered several powerful prognostic indicators, such as the extent of anatomic involvement, histologic pattern, particularly as described by Gleason; and presence or absence of lymphnode metastases. To illustrate the importance of these parameters, the author presents data that correlate survival with the anatomic extent of the primary tumor and the Gleason pattern scores. Of the staged patients, 64 have been subjected to post-therapeutic biopsy of the prostate 18 months or more following therapy. A correlation also seems to exist among clinical stage, lymph node involvement, and subsequent biopsy status. The implication of this finding in the development of more aggressive therapeutic approaches will be discussed.
- Research Organization:
- Stanford Univ. School of Medicine, CA
- OSTI ID:
- 5654205
- Journal Information:
- Urology (Ridgewood, N.J.); (United States), Vol. 25:2 Suppl
- Country of Publication:
- United States
- Language:
- English
Similar Records
Androgen suppression adjuvant to definitive radiotherapy in prostate carcinoma-long-term results of phase III RTOG 85-31
Prognostic Importance of Gleason 7 Disease Among Patients Treated With External Beam Radiation Therapy for Prostate Cancer: Results of a Detailed Biopsy Core Analysis
Related Subjects
CARCINOMAS
RADIOTHERAPY
PROSTATE
BIOPSY
COMPARATIVE EVALUATIONS
LYMPH NODES
METASTASES
PATIENTS
SURVIVAL TIME
BODY
DIAGNOSTIC TECHNIQUES
DISEASES
GLANDS
LYMPHATIC SYSTEM
MALE GENITALS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
RADIOLOGY
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)