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Title: Continuous IBE fermentation by immobilized growing Clostridium beijerinckii cells in a stirred-tank fermentor. [Isopropanol-Butanol-Ethanol (IBE)]

Journal Article · · Biotechnol. Bioeng.; (United States)

The potential of continuous isopropanol-butanol-ethanol (IBE) fermentation by Ca-alginate-immobilized Clostridium beijerinckii cells in a continuous stirred-tank reactor is investigated. A mathematical model is presented to describe steady-state reactor performance. It appeared to be possible to use the biocatalyst particles repeatedly for successive fermentations (at least three times for a total duration of two months). Reactor productivity was 6-16 times higher than that of a batch fermentation (free cells), while the solvents yield was also increased. Measurements of substrate, product, and biomass concentrations were only partially in agreement with the model; however, a solid basis for further technological development of the process has been laid. (Refs. 15).

Research Organization:
Biotech Group, Dept of Chemical Engineering, Delft Univ of Tech, Jaffalaan 9, 2628 BX Delft, The Netherlands
OSTI ID:
5645936
Journal Information:
Biotechnol. Bioeng.; (United States), Vol. 25:1
Country of Publication:
United States
Language:
English