Temporal alignment of tissue and arterial data and selection of integration start times for the H[sub 2] [sup 15]O autoradiographic CBF model in PET
Journal Article
·
· IEEE Transactions on Medical Imaging (Institute of Electrical and Electronics Engineers); (United States)
- Case Western Reserve Univ., Cleveland, OH (United States). Dept. of Biomedical Engineering
- Univ. Hospitals of Cleveland, OH (United States). Div. of Nuclear Medicine
A technique has been developed and tested that provides an automated method of temporally aligning the PET tissue activity curve with the arterial activity curve for quantification of cerebral blood flow using the H[sub 2] [sup 15]O autoradiographic model. This technique not only determines the relative time delay between the two curves, but also provides the start time of integration. Variability in computing global cerebral blood flow using this technique is shown to be less than that obtained by trained observers manually selecting parameters and at least as good as that obtained by using another automated alignment technique.
- OSTI ID:
- 5641368
- Journal Information:
- IEEE Transactions on Medical Imaging (Institute of Electrical and Electronics Engineers); (United States), Vol. 12:3; ISSN 0278-0062
- Country of Publication:
- United States
- Language:
- English
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Tue Dec 31 00:00:00 EST 1996
·
OSTI ID:5641368
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
BRAIN
POSITRON COMPUTED TOMOGRAPHY
CEREBRAL CORTEX
BLOOD FLOW
MATHEMATICAL MODELS
ARTERIES
AUTORADIOGRAPHY
OXYGEN 15
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
CEREBRUM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
ISOTOPES
LIGHT NUCLEI
MINUTES LIVING RADIOISOTOPES
NERVOUS SYSTEM
NUCLEI
ORGANS
OXYGEN ISOTOPES
RADIOISOTOPES
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics
BRAIN
POSITRON COMPUTED TOMOGRAPHY
CEREBRAL CORTEX
BLOOD FLOW
MATHEMATICAL MODELS
ARTERIES
AUTORADIOGRAPHY
OXYGEN 15
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
CEREBRUM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
ISOTOPES
LIGHT NUCLEI
MINUTES LIVING RADIOISOTOPES
NERVOUS SYSTEM
NUCLEI
ORGANS
OXYGEN ISOTOPES
RADIOISOTOPES
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics