Marked increase of calcium uptake in the ATP-depleted red cells of patients with iron deficiency
Journal Article
·
· Am. J. Hematol.; (United States)
Calcium (Ca) uptake was markedly increased in ATP-depleted red cells of patients with iron deficiency anemia (IDA) compared to ATP- depleted normal red cells. The extent of increased Ca uptake was related to the severity of iron deficiency as judged by decreased mean cell volume. Moreover, the increased Ca uptake returned to normal levels after oral iron supplementation therapy. The net calcium content of fresh red cells from iron-deficient individuals was the same as in red cells from normal subjects. Sodium influx and ferric ion uptake appeared to be virtually unaffected in the iron deficient red cells.
- Research Organization:
- Kawasaki Medical School, Kurashiki, Japan
- OSTI ID:
- 5641289
- Journal Information:
- Am. J. Hematol.; (United States), Vol. 19:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CALCIUM
UPTAKE
IRON
NUTRITIONAL DEFICIENCY
ANEMIAS
ATP
ERYTHROCYTES
PATIENTS
SODIUM
ALKALI METALS
ALKALINE EARTH METALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
DISEASES
ELEMENTS
HEMIC DISEASES
MATERIALS
METALS
NUCLEOTIDES
ORGANIC COMPOUNDS
SYMPTOMS
TRANSITION ELEMENTS
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)
CALCIUM
UPTAKE
IRON
NUTRITIONAL DEFICIENCY
ANEMIAS
ATP
ERYTHROCYTES
PATIENTS
SODIUM
ALKALI METALS
ALKALINE EARTH METALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
DISEASES
ELEMENTS
HEMIC DISEASES
MATERIALS
METALS
NUCLEOTIDES
ORGANIC COMPOUNDS
SYMPTOMS
TRANSITION ELEMENTS
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)