Comparison of the physical characteristics of I-131 and I-123, with respect to differentiating the relative activity in the kidneys
Iodine-123 (159 keV, T/sub 1/2/ = 13.3 h) has been proposed for renal investigations, as opposed to I-131 (364 keV, T/sub 1/2/ = 8.06 days), because of its more practical photon energy and lower radiation dose to the patient. The cyclotron production method /sup 124/Te (p,2n) /sup 123/I for I-123 results in contamination with I-124 (T/sub 1/2/ = 4.5 days). The latter emits high-energy photons whole relative abundance increases with time after end of bombardment (EOB). This paper is an evaluation of the effects of photon penetration, scatter, and attenuation on the phantom calibration measurements required for determining relative renal uptake using I-123. Measurments using I-131 were performed for comparison. Phantom results obtained for I-123 suggest that this radionuclide will allow a better measurement of the activity in individual kidneys.
- Research Organization:
- Univ. of Miami, FL
- OSTI ID:
- 5636170
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 24:8
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
61 RADIATION PROTECTION AND DOSIMETRY
62 RADIOLOGY AND NUCLEAR MEDICINE
IODINE 123
UPTAKE
IODINE 131
KIDNEYS
RADIATION DOSES
PHOTONS
ATTENUATION
CALIBRATION
NUCLEAR PHYSICS
PHANTOMS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DOSES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTARY PARTICLES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
MASSLESS PARTICLES
MOCKUP
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PHYSICS
RADIOISOTOPES
STRUCTURAL MODELS
654001* - Radiation & Shielding Physics- Radiation Physics
Shielding Calculations & Experiments
655003 - Medical Physics- Dosimetry
550601 - Medicine- Unsealed Radionuclides in Diagnostics