Immunization of mice with ultraviolet-irradiated Schistosoma mansoni cercariae: a re-evaluation

Journal Article · Fri Jul 01 00:00:00 EDT 1983 · Am. J. Trop. Med. Hyg.; (United States)

OSTI ID:5604999

Dean, D A; Murrell, K D; Xu, S; Mangold, B L

Mice immunized by percutaneous exposure to ultraviolet-irradiated Schistosoma mansoni cercariae developed levels of resistance to subsequent S. mansoni infection comparable to those induced by gamma-irradiated cercariae (50-70% reduction in adult worm burden). Cercariae treated with ultraviolet doses ranging from one to three times the minimum dose required to prevent long-term survival induced the highest levels of resistance.

• Research Organization: Naval Medical Research Institute, Bethesda, Maryland
• OSTI ID: 5604999
• Journal Information: Am. J. Trop. Med. Hyg.; (United States), Vol. 32:4
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
GAMMA RADIATION
BIOLOGICAL RADIATION EFFECTS
COMPARATIVE EVALUATIONS
SCHISTOSOMA
INFECTIVITY
ULTRAVIOLET RADIATION
LARVAE
MICE
ANIMALS
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HELMINTHS
IONIZING RADIATIONS
MAMMALS
PLATYHELMINTHS
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RADIATIONS
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TREMATODES
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560134* - Radiation Effects on Microorganisms- Vaccine Preparation & Other Applications- (-1987)