Clinical application of PET for the evaluation of brain tumors

Journal Article · Mon Apr 01 00:00:00 EST 1991 · Journal of Nuclear Medicine; (United States)

OSTI ID:5603833

Coleman, R E; Hoffman, J M; Hanson, M W; Sostman, H D; Schold, S C ^[1]

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1. Duke Univ. Medical Center, Durham, NC (USA)

The combination of FDG and PET has demonstrated clinical utility in the evaluation of patients with brain tumors. At the time of diagnosis, FDG PET provides information concerning the degree of malignancy and patient prognosis. After therapy, FDG PET is able to assess persistence of tumor, determine degree of malignancy, monitor progression, differentiate recurrence from necrosis, and assess prognosis. Other studies using PET provide information that may be clinically useful. Determination of tumor blood flow and permeability of the blood-brain barrier may help in the selection of appropriate therapy. Amino acid imaging using 11C-methionine is being evaluated in patients with brain tumors and provides different information than FDG imaging.52 references.

• OSTI ID: 5603833
• Journal Information: Journal of Nuclear Medicine; (United States), Vol. 32:4; ISSN 0161-5505
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD-BRAIN BARRIER
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DIAGNOSIS
POSITRON COMPUTED TOMOGRAPHY
DIAGNOSTIC USES
BLOOD FLOW
CARBON 11
FLUORINE ISOTOPES
GLUCOSE
MAN
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CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
HEXOSES
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LIGHT NUCLEI
LIPOTROPIC FACTORS
MAMMALS
MINUTES LIVING RADIOISOTOPES
MONOSACCHARIDES
NERVOUS SYSTEM
NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
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