Radiation sensitivity of small oocytes in immature mice. effect of gonadotropin treatment

Journal Article · Mon Feb 01 00:00:00 EST 1982 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575786· OSTI ID:5579482

Bager, S

The effect of pregnant mare serum gonadotropin on the survival of small oocytes of acutely irradiated immature mice was assessed by counting occytes on serial sections under the light microscope. Twenth-four hours after irradiation with 40 R the number of small oocytes was reduced to a few percent of that in unirradiated controls. The number of oocytes was a little higher in animals injected with gonadotropin before radiation exposure than in animals that were only irradiated. One week after radiation exposure very few small oocytes were seen in any of the irradiated ovaries regardless of treatment. Thus pregnant mare serum gonadotropin had no protective effect on the small oocytes of irradiated immature mice.

• Research Organization: Finsen Inst., Copehagen, Denmark
• OSTI ID: 5579482
• Journal Information: Radiat. Res.; (United States), Vol. 89:2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
GONADOTROPINS
RADIOSENSITIVITY EFFECTS
OOCYTES
BIOLOGICAL RADIATION EFFECTS
MICE
OPTICAL MICROSCOPY
RADIOSENSITIVITY
RESPONSE MODIFYING FACTORS
ANIMALS
BIOLOGICAL EFFECTS
GERM CELLS
HORMONES
MAMMALS
MICROSCOPY
PEPTIDE HORMONES
PITUITARY HORMONES
RADIATION EFFECTS
RODENTS
VERTEBRATES
560121* - Radiation Effects on Cells- External Source- (-1987)