Reversal of acute (''malignant'') myelosclerosis by allogeneic bone marrow transplantation

Journal Article · Fri Jan 01 00:00:00 EST 1982 · Blood; (United States)

OSTI ID:5577956

Wolf, J L; Spruce, W E; Bearman, R M; Forman, S J; Scott, E P; Fahey, J L; Farbstein, M J; Rappaport, H; Blume, K G

A 28-yr-old woman with acute malignant myelosclerosis received, as primary treatment, ablative chemotherapy and total body radiation therapy followed by bone marrow transplantation from her histocompatible brother. The patient is now well more than 15 mo after bone marrow transplantation, with normal peripheral blood counts, a normal bone marrow, no evidence of graft-versus-host disease, and is on no therapy. In light of the poor results obtained with conventional chemotherapy in this disease, bone marrow transplantation may represent the treatment of choice for patients who have an appropriate donor.

• Research Organization: City of Hope National Medical Center, Duarte, CA
• OSTI ID: 5577956
• Journal Information: Blood; (United States), Vol. 59:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BONE MARROW
TRANSPLANTS
NERVOUS SYSTEM DISEASES
RADIOTHERAPY
BIOLOGICAL EFFECTS
BIOLOGICAL RECOVERY
BLOOD
CHEMOTHERAPY
PATIENTS
WHOLE-BODY IRRADIATION
ANIMAL TISSUES
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
DISEASES
EXTERNAL IRRADIATION
HEMATOPOIETIC SYSTEM
IRRADIATION
MATERIALS
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIOLOGY
RECOVERY
THERAPY
TISSUES
550603* - Medicine- External Radiation in Therapy- (1980-)