Diagnosis and management of endocrine gland neoplasms
Functional and nonfunctional neoplasms of the endocrine glands constitute some of the more challenging diagnostic and therapeutic problems in veterinary cancer medicine. The clinical signs are usually the result of an overproduction of hormones that are normally biosynthesized by the neoplastic endocrine gland (orthoendocrine syndromes), as opposed to those that are the result of hormones that are not normally biosynthesized and secreted by those cells that have undergone neoplastic transformation (paraendocrine syndromes, also known as endocrine paraneoplastic syndromes or ectopic hormone syndromes). The biological effects produced by a neoplasm may be out of proportion to the actual size of the tumor. This report focuses on the clinical signs and syndromes associated with neoplasms of the thyroid, adrenal glands and pancreas. Discussion will focus on the mechanisms producing the clinical signs, diagnosis, staging, therapy and prognosis. 2 tabs.
- Research Organization:
- Pacific Northwest Lab., Richland, WA (USA)
- Sponsoring Organization:
- USDOE; USDOE, Washington, DC (USA)
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 5576143
- Report Number(s):
- PNL-SA-17044; CONF-8905379-1; ON: DE91012920
- Resource Relation:
- Conference: 7. annual veterinary medical forum, San Diego, CA (USA), 22-28 May 1989
- Country of Publication:
- United States
- Language:
- English
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Scintigraphic portrayal of the syndrome of multiple endocrine neoplasia type-2B
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
ADRENAL GLANDS
NEOPLASMS
DOGS
ONCOGENIC TRANSFORMATIONS
HORMONES
BIOSYNTHESIS
DIAGNOSIS
PANCREAS
THYROID
VETERINARY MEDICINE
DIAGNOSTIC TECHNIQUES
ADENOMAS
ADRENAL HORMONES
ANIMAL CELLS
CARCINOMAS
INSULIN
IODINE 131
PARATHORMONE
PRODUCTION
THERAPY
THYROID HORMONES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CELL TRANSFORMATIONS
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DISEASES
ENDOCRINE GLANDS
GLANDS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
MAMMALS
MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PEPTIDE HORMONES
RADIOISOTOPES
SYNTHESIS
VERTEBRATES
550600* - Medicine
551000 - Physiological Systems
550200 - Biochemistry