Neoplastic potential of gastric irradiation. IV. Risk estimates
No significant tumor increase was found in the initial analysis of patients irradiated for peptic ulcer and followed through 1962. A preliminary study was undertaken 22 years later to estimate the risk of cancer due to gastric irradiation for peptic ulcer disease. A population of 2,049 irradiated patients and 763 medically managed patients has been identified. A relative risk of 3.7 was found for stomach cancer and an initial risk estimate of 5.5 x 10(-6) excess stomach cancers per person rad was calculated. A more complete follow-up is in progress to further elucidate this observation and decrease the ascertainment bias; however, preliminary data are in agreement with the Japanese atomic bomb reports.
- Research Organization:
- Univ. of Chicago, IL
- OSTI ID:
- 5555620
- Journal Information:
- Am. J. Clin. Oncol.; (United States), Vol. 7:6
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
NEOPLASMS
RISK ASSESSMENT
RADIOTHERAPY
SIDE EFFECTS
STOMACH
ULCERS
PATIENTS
RADIATION DOSES
STATISTICAL DATA
TIME DEPENDENCE
BODY
DATA
DIGESTIVE SYSTEM
DISEASES
DOSES
GASTROINTESTINAL TRACT
INFORMATION
MEDICINE
NUCLEAR MEDICINE
NUMERICAL DATA
ORGANS
PATHOLOGICAL CHANGES
RADIOLOGY
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man