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Title: Neoplastic potential of gastric irradiation. IV. Risk estimates

Journal Article · · Am. J. Clin. Oncol.; (United States)

No significant tumor increase was found in the initial analysis of patients irradiated for peptic ulcer and followed through 1962. A preliminary study was undertaken 22 years later to estimate the risk of cancer due to gastric irradiation for peptic ulcer disease. A population of 2,049 irradiated patients and 763 medically managed patients has been identified. A relative risk of 3.7 was found for stomach cancer and an initial risk estimate of 5.5 x 10(-6) excess stomach cancers per person rad was calculated. A more complete follow-up is in progress to further elucidate this observation and decrease the ascertainment bias; however, preliminary data are in agreement with the Japanese atomic bomb reports.

Research Organization:
Univ. of Chicago, IL
OSTI ID:
5555620
Journal Information:
Am. J. Clin. Oncol.; (United States), Vol. 7:6
Country of Publication:
United States
Language:
English