The role of neutron activation analysis in nutritional biomonitoring programs
Nutritional biomonitoring is a multidisciplinary task and an integral part of a more general bioenvironmental surveillance. In its comprehensive form, it is a combination of biological, environmental, and nutrient monitoring activities. Nutrient monitoring evaluates the input of essential nutrients required to maintain vital bodily functions; this includes vigilance over extreme fluctuations of nutrient intake in relation to the recommended dietary allowances and estimated safe and adequate daily dietary intakes and adherence to the goals of provisional tolerance limits. Environmental monitoring assesses the external human exposure via ambient pathways, namely, air, water, soil, food, etc. Biological monitoring quantifies a toxic agent and its metabolites in representative biologic specimens of an exposed organ to identify health effects. In practice, coordinating all three components of a nutritional biomonitoring program is complex, expensive, and tedious. Experience gained from the US National Health and Nutrition Examination Surveys demonstrates the problems involved. By far the most critical challenge faced here is the question of analytical quality control, particularly when trace element determinations are involved. Yet, measures to ensure reliability of analytical data are mandatory, and there are no short-cuts to this requirement. The purpose of this presentation is to elucidate the potential of neutron activation analysis (NAA) in nutritional biomonitoring activities.
- OSTI ID:
- 5554757
- Report Number(s):
- CONF-880601-; CODEN: TANSA; TRN: 89-026608
- Journal Information:
- Transactions of the American Nuclear Society; (USA), Vol. 56; Conference: American Nuclear Society annual meeting, San Diego, CA (USA), 12-16 Jun 1988; ISSN 0003-018X
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
BIOLOGICAL MATERIALS
ACTIVATION ANALYSIS
DIET
MONITORING
MAN
ARSENIC
CADMIUM
CHROMIUM
COPPER
ENVIRONMENTAL EXPOSURE PATHWAY
IODINE
IRON
LEAD
MANGANESE
MERCURY
METABOLITES
MOLYBDENUM
NUTRIENTS
NUTRITION
QUALITY CONTROL
SELENIUM
TIN
ZINC
ANIMALS
CHEMICAL ANALYSIS
CONTROL
ELEMENTS
HALOGENS
MAMMALS
MATERIALS
METALS
NONMETALS
PRIMATES
SEMIMETALS
TRANSITION ELEMENTS
VERTEBRATES
400101* - Activation
Nuclear Reaction
Radiometric & Radiochemical Procedures