In vitro radiosensitivity of human leukemia cell lines

Journal Article · Fri May 01 00:00:00 EDT 1981 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.139.2.6939019· OSTI ID:5549324

Weichselbaum, R R; Greenberger, J S; Schmidt, A; Karpas, A; Moloney, W C; Little, J B

The in vitro radiobiologic survival values (n, D0) of four tumor lines derived from human hematopoietic tumors were studied. These cell lines were HL50 (n . 1.3, D0 . 117 rad(1.17 Gy)), promyelocytic leukemia; K562 (n . 1.4, D0 . 165 rad(1.65 Gy)), erythroleukemia; 45 (n . 1.1, D0 . 147 rad(1.47 Gy)), acute lymphocyte leukemia; and 176 (n . 4.0, D0 . 76 rad(0.76 Gy)), acute monomyelogenous leukemia. More cell lines must be examined before the exact relationship between in vitro radiosensitivity and clinical radiocurability is firmly established.

• OSTI ID: 5549324
• Journal Information: Radiology; (United States), Vol. 139:2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
LEUKEMIA
BIOLOGICAL RADIATION EFFECTS
TUMOR CELLS
RADIOSENSITIVITY
CELL CULTURES
COMPARATIVE EVALUATIONS
DOSE-RESPONSE RELATIONSHIPS
IN VITRO
MAN
RADIATION DOSES
SURVIVAL CURVES
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
DISEASES
DOSES
HEMIC DISEASES
MAMMALS
NEOPLASMS
PRIMATES
RADIATION EFFECTS
VERTEBRATES
560121* - Radiation Effects on Cells- External Source- (-1987)
550603 - Medicine- External Radiation in Therapy- (1980-)