The management of breast carcinoma by primary radiotherapy of Mount Sinai hospital from 1962-1979. [/sup 60/Co; Betatron]

Journal Article · Thu Apr 15 00:00:00 EST 1982 · Cancer (Philadelphia); (United States)

DOI:https://doi.org/10.1002/1097-0142(19820415)49:8<1587::AID-CNCR2820490811>3.0.CO;2-K· OSTI ID:5528926

Balawajder, I; Antich, P P; Boland, J

Two-hundred eight patients with carcinoma of the breast were treated with megavoltage irradiation as the primary method of local management at Mount Sinai Hospital between 1962-1979. The effects of treatment volume, technique, and other parameters are discussed for the Stage I and II patients, together with the importance of tumor size and nodal status in control of local disease and distant metastases. In this series the cumulative probability of freedom from metastases is 93 +/- 5% when the irradiation is confined to the breast and axilla as compared with 72 +/- 9% when extended fields are used, with no difference in local control. Based on these results it was decided to confine irradiation to the breast and axilla alone in the majority of early stage cancer patients. Recommendations are made for radiation techniques and dosages to optimize control of the disease, minimize complications, and facilitate systemic therapy in patients with positive nodes.

• Research Organization: Mount Sinai School of Medicine, New York, NY
• OSTI ID: 5528926
• Journal Information: Cancer (Philadelphia); (United States), Vol. 49:8
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
ERYTHEMA
RADIOINDUCTION
FIBROSIS
MAMMARY GLANDS
BIOLOGICAL RADIATION EFFECTS
RADIOTHERAPY
SIDE EFFECTS
SKIN
CARCINOMAS
COBALT 60
DOSE-RESPONSE RELATIONSHIPS
GAMMA RADIATION
HARD X RADIATION
PATIENTS
RADIATION DOSES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
COBALT ISOTOPES
DISEASES
DOSES
ELECTROMAGNETIC RADIATION
GLANDS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOLOGY
SYMPTOMS
THERAPY
X RADIATION
YEARS LIVING RADIOISOTOPES
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)