Radiotherapeutic prophylaxis of estrogen-induced gynecomastia: a study of late sequela

Journal Article · Sat Mar 01 00:00:00 EST 1986 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(86)90359-7· OSTI ID:5528593

Fass, D; Steinfeld, A; Brown, J; Tessler, A

Radiation therapy is an effective means of preventing the development of hormone-induced gynecomastia in men with cancer of the prostate. The efficacy and morbidity of this type of radiation was studied in a retrospective analysis of 87 patients referred for treatment from 1972 to 1982. Patients receiving DES as treatment for prostate carcinoma were treated with irradiation to the breast tissue. Patients were treated with 4 MV, 60Co superficial X rays. Doses range from 1200 to 1500 cGy in 3 fractions. The majority of patients had satisfactory results in terms of prevention of gynecomastia and mammalgia. There were few acute reactions noted and no evidence of long term sequela.

• Research Organization: New York Univ. Medical Center, NY
• OSTI ID: 5528593
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 3
• Country of Publication: United States
• Language: English

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