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Title: Iodine neutron capture therapy: A new generation of radiotherapy for the thyroid

Journal Article · · Transactions of the American Nuclear Society
OSTI ID:552350
; ; ; ;  [1]
  1. Idaho State Univ., Pocatello, ID (United States)

An innovative technique is being pursued that takes advantage of noninvasive, in situ neutron capture therapy concepts for treating hyperthyroidism and thyroid carcinoma. Present treatment techniques include surgical removal of the thyroid or, more frequently, the oral administration of {sup 131}I. Therapeutic applications of {sup 131}I are complicated by the unavoidable and undesirable exposure of ancillary body organs, protracted treatment times due to long effective half-life, and less than ideal radiation emission characteristics, i.e., low-effective energy available for deposition in the target organ. These problems are mitigated through the use of {sup 128}I. Table I provides pertinent radiological characteristics for a comparison of {sup 131}I with {sup 128}I.

OSTI ID:
552350
Report Number(s):
CONF-971125-; ISSN 0003-018X; TRN: 97:005809-0040
Journal Information:
Transactions of the American Nuclear Society, Vol. 77; Conference: 1997 American Nuclear Society (ANS) winter meeting, Albuquerque, NM (United States), 16-20 Nov 1997; Other Information: PBD: 1997
Country of Publication:
United States
Language:
English