A case-control study of chemical exposures and brain tumors in petrochemical workers
The relationship between chemical exposures and deaths attributable to primary brain tumors among employees of a Texas petrochemical plant was investigated. Cases consisted of 21 deaths in which the underlying cause was confirmed as a primary brain tumor. Two control groups of 80 employees each were randomly selected from 450 decedents known to the company in June, 1979. Potential exposures while employed were compared between cases and controls for five known or suspect carcinogens. Exposure potentials were also compared for an additional 37 chemicals to which at least four cases were potentially exposed. Overall and 15-year latency analyses were performed. The proportion of cases exposed to the five potentially carcinogenic chemicals (including vinyl chloride) were lower than or consistent with the proportion of exposed controls. No statistically significant differences between the proportions of cases and controls exposed to the 37 other chemicals were found.
- Research Organization:
- Department of Epidemiology, Union Carbide Corporation, Danbury, CT
- OSTI ID:
- 5522209
- Journal Information:
- JOM, J. Occup. Med.; (United States), Vol. 25:4
- Country of Publication:
- United States
- Language:
- English
Similar Records
Brain cancer in petrochemical workers: a case series report
A cohort mortality study of petrochemical workers
Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BRAIN
NEOPLASMS
PETROCHEMICAL PLANTS
OCCUPATIONAL DISEASES
PETROCHEMICALS
CARCINOGENESIS
EPIDEMIOLOGY
TEXAS
BODY
CENTRAL NERVOUS SYSTEM
CHEMICAL PLANTS
DISEASES
FEDERAL REGION VI
INDUSTRIAL PLANTS
NERVOUS SYSTEM
NORTH AMERICA
ORGANS
PATHOGENESIS
PETROLEUM PRODUCTS
USA
020600* - Petroleum- Health & Safety
560306 - Chemicals Metabolism & Toxicology- Man- (-1987)