Use of /sup 51/Cr-labeled mononuclear cells for measuring the cellular immune response in mouse lungs
Journal Article
·
· Infect. Immun.; (United States)
OSTI ID:5505160
Spleen cells labeled with /sup 51/Cr were used in sensitized syngeneic mice to measure the degree of mononuclear cell infiltration into antigen-challenged tissues. With this method, increased cellular infiltration was found after footpad challenge of mice sensitized with sheep erythrocyte, Escherichia coli, and BCG antigens. Cellular response also was determined by using this technique in the lungs of mice sensitized with sheep erythrocytes and BCG. This procedure offers the opportunity to measure cellular infiltration, whether due to cellular or humoral influences, in tissues not easily accessible to conventional immunological manipulation.
- OSTI ID:
- 5505160
- Journal Information:
- Infect. Immun.; (United States), Vol. 31:2
- Country of Publication:
- United States
- Language:
- English
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+3 more
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
CHROMIUM 51
ISOTOPE APPLICATIONS
MONOCYTES
BIOLOGICAL FUNCTIONS
ANTIGEN-ANTIBODY REACTIONS
ANTIGENS
IMMUNE REACTIONS
LABELLED COMPOUNDS
LUNGS
MICE
SPLEEN CELLS
ANIMAL CELLS
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CHROMIUM ISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
FUNCTIONS
INTERMEDIATE MASS NUCLEI
ISOTOPES
LEUKOCYTES
MAMMALS
MATERIALS
NUCLEI
ORGANS
RADIOISOTOPES
RESPIRATORY SYSTEM
RODENTS
SOMATIC CELLS
VERTEBRATES
550301* - Cytology- Tracer Techniques
551001 - Physiological Systems- Tracer Techniques
CHROMIUM 51
ISOTOPE APPLICATIONS
MONOCYTES
BIOLOGICAL FUNCTIONS
ANTIGEN-ANTIBODY REACTIONS
ANTIGENS
IMMUNE REACTIONS
LABELLED COMPOUNDS
LUNGS
MICE
SPLEEN CELLS
ANIMAL CELLS
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CHROMIUM ISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
FUNCTIONS
INTERMEDIATE MASS NUCLEI
ISOTOPES
LEUKOCYTES
MAMMALS
MATERIALS
NUCLEI
ORGANS
RADIOISOTOPES
RESPIRATORY SYSTEM
RODENTS
SOMATIC CELLS
VERTEBRATES
550301* - Cytology- Tracer Techniques
551001 - Physiological Systems- Tracer Techniques