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Title: In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes

Abstract

Porcine carrier erythrocyte survival was measured in adult pigs. (14C)Sucrose-loaded erythrocytes had a biphasic survival curve, with as much as 50% of the cells removed from circulation in the first 24 hours. The remaining cells had a 35-day half-life. Encapsulation values were measured for porcine erythrocytes and entrapment of (14C)sucrose was greater than 45%. Addition of inosine and glucose to the dialyzed cells and to the final wash buffer before reinjection of autologous cells did not improve their survival.

Authors:
Publication Date:
Research Org.:
Veterinary Toxicology and Entomology Research Laboratory, US Department of Agriculture, College Station, TX
OSTI Identifier:
5502689
Resource Type:
Journal Article
Journal Name:
Am. J. Vet. Res.; (United States)
Additional Journal Information:
Journal Volume: 44:6
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; ERYTHROCYTES; BIOLOGICAL HALF-LIFE; ADULTS; CARBON 14; SACCHAROSE; SURVIVAL TIME; SWINE; VETERINARY MEDICINE; AGE GROUPS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CARBOHYDRATES; CARBON ISOTOPES; DISACCHARIDES; DOMESTIC ANIMALS; EVEN-EVEN NUCLEI; ISOTOPES; LIGHT NUCLEI; MAMMALS; MATERIALS; MEDICINE; NUCLEI; OLIGOSACCHARIDES; ORGANIC COMPOUNDS; RADIOISOTOPES; SACCHARIDES; VERTEBRATES; YEARS LIVING RADIOISOTOPES; 553001* - Agriculture & Food Technology- Tracer Techniques- (-1987)

Citation Formats

DeLoach, J R. In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes. United States: N. p., 1983. Web.
DeLoach, J R. In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes. United States.
DeLoach, J R. 1983. "In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes". United States.
@article{osti_5502689,
title = {In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes},
author = {DeLoach, J R},
abstractNote = {Porcine carrier erythrocyte survival was measured in adult pigs. (14C)Sucrose-loaded erythrocytes had a biphasic survival curve, with as much as 50% of the cells removed from circulation in the first 24 hours. The remaining cells had a 35-day half-life. Encapsulation values were measured for porcine erythrocytes and entrapment of (14C)sucrose was greater than 45%. Addition of inosine and glucose to the dialyzed cells and to the final wash buffer before reinjection of autologous cells did not improve their survival.},
doi = {},
url = {https://www.osti.gov/biblio/5502689}, journal = {Am. J. Vet. Res.; (United States)},
number = ,
volume = 44:6,
place = {United States},
year = {Wed Jun 01 00:00:00 EDT 1983},
month = {Wed Jun 01 00:00:00 EDT 1983}
}