In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes
Abstract
Porcine carrier erythrocyte survival was measured in adult pigs. (14C)Sucrose-loaded erythrocytes had a biphasic survival curve, with as much as 50% of the cells removed from circulation in the first 24 hours. The remaining cells had a 35-day half-life. Encapsulation values were measured for porcine erythrocytes and entrapment of (14C)sucrose was greater than 45%. Addition of inosine and glucose to the dialyzed cells and to the final wash buffer before reinjection of autologous cells did not improve their survival.
- Authors:
- Publication Date:
- Research Org.:
- Veterinary Toxicology and Entomology Research Laboratory, US Department of Agriculture, College Station, TX
- OSTI Identifier:
- 5502689
- Resource Type:
- Journal Article
- Journal Name:
- Am. J. Vet. Res.; (United States)
- Additional Journal Information:
- Journal Volume: 44:6
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES; ERYTHROCYTES; BIOLOGICAL HALF-LIFE; ADULTS; CARBON 14; SACCHAROSE; SURVIVAL TIME; SWINE; VETERINARY MEDICINE; AGE GROUPS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CARBOHYDRATES; CARBON ISOTOPES; DISACCHARIDES; DOMESTIC ANIMALS; EVEN-EVEN NUCLEI; ISOTOPES; LIGHT NUCLEI; MAMMALS; MATERIALS; MEDICINE; NUCLEI; OLIGOSACCHARIDES; ORGANIC COMPOUNDS; RADIOISOTOPES; SACCHARIDES; VERTEBRATES; YEARS LIVING RADIOISOTOPES; 553001* - Agriculture & Food Technology- Tracer Techniques- (-1987)
Citation Formats
DeLoach, J R. In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes. United States: N. p., 1983.
Web.
DeLoach, J R. In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes. United States.
DeLoach, J R. 1983.
"In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes". United States.
@article{osti_5502689,
title = {In vivo survival of (14C)sucrose-loaded porcine carrier erythrocytes},
author = {DeLoach, J R},
abstractNote = {Porcine carrier erythrocyte survival was measured in adult pigs. (14C)Sucrose-loaded erythrocytes had a biphasic survival curve, with as much as 50% of the cells removed from circulation in the first 24 hours. The remaining cells had a 35-day half-life. Encapsulation values were measured for porcine erythrocytes and entrapment of (14C)sucrose was greater than 45%. Addition of inosine and glucose to the dialyzed cells and to the final wash buffer before reinjection of autologous cells did not improve their survival.},
doi = {},
url = {https://www.osti.gov/biblio/5502689},
journal = {Am. J. Vet. Res.; (United States)},
number = ,
volume = 44:6,
place = {United States},
year = {Wed Jun 01 00:00:00 EDT 1983},
month = {Wed Jun 01 00:00:00 EDT 1983}
}
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