Understanding and predicting protein structure

Conference · Tue Dec 31 04:00:00 UTC 1996

OSTI ID:549233

Fischer, D ^[1]; Godzik, A ^[2]; Chung, S ^[3]

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1. Univ. of California, Los Angeles, CA (United States)
2. Scripps Research Institute, La Jolla, CA (United States)
3. Uniformed Services Univ. of the Health Sciences, Bethesda, MD (United States); and others

Protein structure prediction from sequence remains a premiere computational problem for modern molecular biology. Just as protein structure prediction may be divided into sub-problems of main-chain and side-chain placement, so the protein structure prediction track this year has been divided into sub-tracks of protein threading (organized by Daniel Fischer and Adam Godzik) and side-chain packing (organized by Su Chung and S. Subbiah). The result is an unusually rich tour through different levels of protein structure prediction, from coarse-grained prediction of the tertiary fold to the fine-grained atomic detail of individual side-chains. 8 refs.

• DOE Contract Number: FG03-95ER62135
• OSTI ID: 549233
• Report Number(s): CONF-970132--
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
99 GENERAL AND MISCELLANEOUS
ALGORITHMS
AMINO ACID SEQUENCE
BIOLOGICAL EVOLUTION
DNA SEQUENCING
ELECTRONIC STRUCTURE
EVALUATION
FAILURE MODE ANALYSIS
GENETIC MAPPING
MOLECULAR BIOLOGY
MUTATIONS
PARAMETRIC ANALYSIS
PROTEIN STRUCTURE
PROTEINS
RESOLUTION
STRUCTURAL MODELS
STRUCTURE-ACTIVITY RELATIONSHIPS