DNA repair synthesis in the rat retina following in vivo exposure to 300-nm radiation

Journal Article · Fri Mar 01 00:00:00 EST 1985 · Invest. Ophthalmol. Visual Sci.; (United States)

OSTI ID:5480028

Rapp, L M; Jose, J G; Pitts, D G

Quantitative autoradiography was used to study the incorporation of /sup 3/H-thymidine into the retina of albino rats following in vivo exposure to 300-nm radiation. Relative to background labeling in unexposed eyes, there was 8-20 times as much label per unit area in the outer nuclear layer, inner nuclear layer, and ganglion cells of 300-nm exposed retinas. The photoreceptor inner segments also showed thymidine labeling in both control and exposed retinas.

• Research Organization: Baylor College of Medicine, Houston, TX
• OSTI ID: 5480028
• Journal Information: Invest. Ophthalmol. Visual Sci.; (United States), Vol. 26:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
DNA REPAIR
RETINA
AUTORADIOGRAPHY
BIOLOGICAL RADIATION EFFECTS
NERVE CELLS
RATS
THYMIDINE
TRACER TECHNIQUES
TRITIUM COMPOUNDS
ULTRAVIOLET RADIATION
ANIMAL CELLS
ANIMALS
AZINES
BIOLOGICAL EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BODY
BODY AREAS
ELECTROMAGNETIC RADIATION
EYES
FACE
HEAD
HETEROCYCLIC COMPOUNDS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MAMMALS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PYRIMIDINES
RADIATION EFFECTS
RADIATIONS
RECOVERY
REPAIR
RIBOSIDES
RODENTS
SENSE ORGANS
SOMATIC CELLS
VERTEBRATES
560121* - Radiation Effects on Cells- External Source- (-1987)