Enhanced withdrawal of polychlorinated biphenyls: A comparison of colestipol, mineral oil, propylene glycol, and petroleum jelly with or without restricted feeding
- Michigan State Univ., East Lansing (USA)
Meat type chickens were fed a commercial mixture of polychlorinated biphenyl (PCB), Aroclor 1254, at 10 ppm for 14 days, then treated for 21 days to hasten the withdrawal of PCB with either mineral oil (MO), petroleum jelly (PJ), propylene glycol (PG), or colestipol (CO) at 5% of the diet, or at 10% of the diet when restricted to 50% of control intake (50% FR). Whole carcass analyses for PCB revealed that MO + 50% FR reduced PCB to 1.91 mg/bird, or 32% of the body burden (5.96 mg) in nontreated chickens previously fed PCB, whereas those restricted in feed intake by 50% (50% FR) had almost no change (6.44 mg/bird) in body burdens. The PJ, PG, and CO in combination with 50% FR reduced body burdens of PCB to 47, 57, and 77%, respectively, of the control value. When treated with MO, PJ, PG, or CO alone (no 50% FR), chickens had body burdens reduced to only 67 to 90% of control, depending on th compound. Thus, feed restriction was necessary for the MO and PJ to have their greatest effect. Carcass lipid values and body weight gains were markedly reduced by the feed restriction. The CO reduced carcass lipid in nonrestricted chickens by 30%.
- OSTI ID:
- 5477638
- Journal Information:
- Poultry Science; (USA), Vol. 68:7; ISSN 0032-5791
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
CHLORINATED AROMATIC HYDROCARBONS
BODY BURDEN
ANIMAL FEEDS
CHICKENS
LIPIDS
MINERAL OILS
ANIMALS
AROMATICS
BIRDS
FOOD
FOWL
HALOGENATED AROMATIC HYDROCARBONS
OILS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
OTHER ORGANIC COMPOUNDS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology