Humoral and cell-mediated immune function in adult Japanese Quail following exposure to 2. 45-GHz microwave radiation during embryogeny

Journal Article · Thu Jan 01 00:00:00 EST 1981 · Bioelectromagnetics (N.Y.); (United States)

DOI:https://doi.org/10.1002/bem.2250020308· OSTI ID:5454776

Galvin, M J; McRee, D I; Hall, C A; Thaxton, J P; Parkhurst, C R

Japanese quail, Coturnix coturnix japonica, eggs were subjected to 2.45-GHz CW microwave radiation at 5 mW/cm2 (SAR . 4.03 mW/g) during the first 12 days of embryogeny. Following hatching the exposed embryos, as well as nonexposed controls, were reared to 22 weeks of age. Humoral immune potential, as indicated by comparable anti-CRBC antibody, IgM and IgG, levels at 0, 4, and 7 days postimmunization in both exposed and control quail was not affected significantly. However, cell-mediated immune potential, measured by the reaction to intradermal injection of phytohemagglutinin-P in the wing web, was reduced in the exposed females, but not in the exposed males. Additionally, total leukocyte numbers and absolute circulating numbers of lymphocytes, monocytes, and heterophils were increased significantly only in the exposed females. These data show that exposure of Japanese quail during embryogenesis reduced cell mediated immune potential and induced a general leukocytosis in females.

• Research Organization: National Institute of Environmental Health Sciences, Research Triangle Park, NC
• OSTI ID: 5454776
• Journal Information: Bioelectromagnetics (N.Y.); (United States), Vol. 2:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
EGGS
SENSITIVITY
MICROWAVE RADIATION
BIOLOGICAL EFFECTS
ANTIGEN-ANTIBODY REACTIONS
BIRDS
EMBRYOS
LYMPHOCYTES
MONOCYTES
PHYTOHEMAGGLUTININ
SEX DEPENDENCE
AGGLUTININS
ANIMAL CELLS
ANIMALS
ANTIBODIES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOHYDRATES
CONNECTIVE TISSUE CELLS
ELECTROMAGNETIC RADIATION
HEMAGGLUTININS
LEUKOCYTES
MATERIALS
MITOGENS
MUCOPROTEINS
ORGANIC COMPOUNDS
POLYSACCHARIDES
PROTEINS
RADIATIONS
SACCHARIDES
SOMATIC CELLS
VERTEBRATES
560400* - Other Environmental Pollutant Effects