Isolation of a protein kinase induced by herpes simplex virus type 1

Journal Article · Wed Apr 01 00:00:00 EST 1981 · J. Virol.; (United States)

OSTI ID:5451630

Blue, W T; Stobbs, D G

Researchers have isolated a new cyclic AMP-independent protein kinase activity induced in HeLa cells by infection with herpes simplex virus type 1. Induction of the enzyme does not occur in cells treated with cycloheximide at the time of infection, or in cells infected with UV-inactivated herpes simplex virus type 1. The amount of enzyme induced in infected cells is dependent upon the multiplicity of infection. An enzyme with identical properties to the appearing in infected HeLa cells is also induced by herpes simplex virus type 1 in BHK cells.

• OSTI ID: 5451630
• Journal Information: J. Virol.; (United States), Vol. 38:1
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
HERPES SIMPLEX
BIOLOGICAL EFFECTS
PHOSPHOTRANSFERASES
ENZYME ACTIVITY
QUANTITATIVE CHEMICAL ANALYSIS
BIOCHEMICAL REACTION KINETICS
CELL CULTURES
CHEMICAL PROPERTIES
COMPARATIVE EVALUATIONS
CYCLOHEXIMIDE
PROTEINS
QUANTITY RATIO
ULTRAVIOLET RADIATION
ANTI-INFECTIVE AGENTS
ANTIBIOTICS
CHEMICAL ANALYSIS
DISEASES
DRUGS
ELECTROMAGNETIC RADIATION
ENZYMES
FUNGICIDES
INFECTIOUS DISEASES
KINETICS
ORGANIC COMPOUNDS
PESTICIDES
PHOSPHORUS-GROUP TRANSFERASES
RADIATIONS
REACTION KINETICS
SKIN DISEASES
TRANSFERASES
VIRAL DISEASES
550200* - Biochemistry
550700 - Microbiology