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Title: Relative decreased splenic uptake of Tc-99m-sulfur colloid in patients with pancreatic carcinoma

Abstract

Relative spleen/liver activity ratio was determined from posterior projection images using a photodensitometric method. Ratios from scans of 22 patients with proven pancreatic carcinoma (12 from rectilinear scans and 10 from scintillation camera images) were determined and compared to studies from patients documented as normal and to randomly selected liver/spleen imaging studies which had been previously interpreted as normal. The mean ratio from the pancreatic carcinoma group was significantly lower than the means of the respective normal groups (p(t) less than .0001 for rectilinear scans and p(t) less than .001 for scintigrams). There was no significant difference between the means of the proven normal and randomly selected normal groups or between the two pancreatic carcinoma groups. Splenic vascular alteration is discussed as a possible reason for decreased splenic distribution of Tc-99m-sulfur colloid in this patient group.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Department of Radiology, Virginia Commonwealth University, Medical College of Virginia, Richmond
OSTI Identifier:
5450956
Resource Type:
Journal Article
Journal Name:
Clin. Nucl. Med.; (United States)
Additional Journal Information:
Journal Volume: 7:1
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; PANCREAS; NEOPLASMS; ADOLESCENTS; CHILDREN; ELDERLY PEOPLE; HUMAN POPULATIONS; ISOMERIC NUCLEI; LIVER; PATIENTS; SCINTISCANNING; SPLEEN; TECHNETIUM 99; UPTAKE; AGE GROUPS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; ENDOCRINE GLANDS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MINORITY GROUPS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; POPULATIONS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Tatum, J L, Burke, T S, Fratkin, M J, Sharpe, Jr, A R, and Goodrich, J K. Relative decreased splenic uptake of Tc-99m-sulfur colloid in patients with pancreatic carcinoma. United States: N. p., 1982. Web. doi:10.1097/00003072-198201000-00001.
Tatum, J L, Burke, T S, Fratkin, M J, Sharpe, Jr, A R, & Goodrich, J K. Relative decreased splenic uptake of Tc-99m-sulfur colloid in patients with pancreatic carcinoma. United States. https://doi.org/10.1097/00003072-198201000-00001
Tatum, J L, Burke, T S, Fratkin, M J, Sharpe, Jr, A R, and Goodrich, J K. 1982. "Relative decreased splenic uptake of Tc-99m-sulfur colloid in patients with pancreatic carcinoma". United States. https://doi.org/10.1097/00003072-198201000-00001.
@article{osti_5450956,
title = {Relative decreased splenic uptake of Tc-99m-sulfur colloid in patients with pancreatic carcinoma},
author = {Tatum, J L and Burke, T S and Fratkin, M J and Sharpe, Jr, A R and Goodrich, J K},
abstractNote = {Relative spleen/liver activity ratio was determined from posterior projection images using a photodensitometric method. Ratios from scans of 22 patients with proven pancreatic carcinoma (12 from rectilinear scans and 10 from scintillation camera images) were determined and compared to studies from patients documented as normal and to randomly selected liver/spleen imaging studies which had been previously interpreted as normal. The mean ratio from the pancreatic carcinoma group was significantly lower than the means of the respective normal groups (p(t) less than .0001 for rectilinear scans and p(t) less than .001 for scintigrams). There was no significant difference between the means of the proven normal and randomly selected normal groups or between the two pancreatic carcinoma groups. Splenic vascular alteration is discussed as a possible reason for decreased splenic distribution of Tc-99m-sulfur colloid in this patient group.},
doi = {10.1097/00003072-198201000-00001},
url = {https://www.osti.gov/biblio/5450956}, journal = {Clin. Nucl. Med.; (United States)},
number = ,
volume = 7:1,
place = {United States},
year = {Fri Jan 01 00:00:00 EST 1982},
month = {Fri Jan 01 00:00:00 EST 1982}
}