Increased blood and urine copper after residential exposure to copper naphthenate

Journal Article · Wed Jan 01 00:00:00 EST 1992 · Journal of Toxicology, Clinical Toxicology; (United States)

DOI:https://doi.org/10.3109/15563659208994449· OSTI ID:5441046

Bluhm, R E; Welch, L; Branch, R A ^[1]

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1. Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN (United States)

Despite widespread industrial use of copper naphthenate, there are no reports of the relationship of copper naphthenate and copper absorption in humans or animals. We report a family of three individuals who lived in a home where copper naphthenate was sprayed on the inner foundation. Subsequently, these individuals developed non-specific complaints. In two of these individuals, serum copper levels were elevated when first measured months after copper naphthenate was sprayed in the home. A gradual decline over several years in urine and serum copper levels was observed in the individual who maintained follow-up. It is not known if symptoms reflected exposure to naphthenate, the solvent vehicle, volatilized copper, or the stress of exposure to a malodorous compound perceived as toxic. Exposure to copper naphthenate may be another cause of an elevated serum and urine copper level but the interpretation of these levels as normal' or toxic' requires additional study for clarification. This report suggests the need for further study of the absorption and relative toxicity of copper naphthenate.

• OSTI ID: 5441046
• Journal Information: Journal of Toxicology, Clinical Toxicology; (United States), Vol. 30:1; ISSN 0731-3810
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
COPPER
TOXICITY
ABSORPTION
CARBOXYLIC ACIDS
CONJUNCTIVITIS
ENVIRONMENTAL EXPOSURE
MAN
METABOLISM
NAUSEA
RESIDENTIAL BUILDINGS
VOMITING
ANIMALS
BUILDINGS
DISEASES
ELEMENTS
MAMMALS
METALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
PRIMATES
SENSE ORGANS DISEASES
SYMPTOMS
TRANSITION ELEMENTS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology