Improved protein labeling by stannous tartrate reduction of pertechnetate

Journal Article · Tue Jan 01 00:00:00 EST 1980 · J. Nucl. Med.; (United States)

OSTI ID:5437065

Pettit, W A; DeLand, F H; Bennett, S J; Goldenberg, D M

A procedure has been developed whereby small amounts of protein - specifically human serum albumin and immunoglobulin G - can be labeled with Tc-99m. Artifactual problems associated with electrolytic and stannous chloride labeling procedures are virtually eliminated. The procedure is satisfactory for labeling human serum albumin, normal goat immunoglobulin G, and goat anti-carcinoembryonic antigen immunoglobulin G.

• Research Organization: Veteran's Administration Medical Center, Lexington, KY
• OSTI ID: 5437065
• Journal Information: J. Nucl. Med.; (United States), Vol. 21:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
ALBUMINS
LABELLING
IMMUNOGLOBULINS
TECHNETIUM 99
TRACER TECHNIQUES
CHEMICAL PREPARATION
EXTRACTION CHROMATOGRAPHY
ISOMERIC NUCLEI
PERTECHNETATES
REDUCTION
TARTRATES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CARBOXYLIC ACID SALTS
CHEMICAL REACTIONS
CHROMATOGRAPHY
GLOBULINS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
PROTEINS
RADIOISOTOPES
SEPARATION PROCESSES
SYNTHESIS
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
400702 - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials