Iodine-125 radiation of posterior uveal melanoma

Journal Article · Tue Dec 01 00:00:00 EST 1987 · Ophthalmology (Rochester, Minn.); (United States)

DOI:https://doi.org/10.1016/S0161-6420(87)33241-5· OSTI ID:5432978

Packer, S

Twenty-eight cases of posterior choroidal melanoma were treated with iodine-125 in gold eye plaques. Eleven cases were located within 3.0 mm of the optic nerve (group A), nine were within 3.0 mm of the fovea (group B), and eight were within 3.0 mm of the optic nerve and fovea (group C). The mean follow-up of group A was 46.3 months; group B, 25.5 months; and group C, 42.7 months. Complications included macular edema, cataract and tumor growth. Visual acuity remained within two lines of that tested preoperatively for 4 of 11 patients in group A, 4 of 9 in group B, and 5 of 8 in group C. These results with iodine-125 suggest it as an appropriate treatment for patients with choroidal melanoma located near optic nerve and/or macula.

• Research Organization: North Shore Univ. Hospital, Manhasset, NY (USA)
• OSTI ID: 5432978
• Journal Information: Ophthalmology (Rochester, Minn.); (United States), Vol. 94:12
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
MELANOMAS
RADIOTHERAPY
UVEA
EDEMA
GOLD
IODINE 125
PATIENTS
RADIATION INJURIES
VISION
BETA DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
EYES
FACE
HEAD
INJURIES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPES
MEDICINE
METALS
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIOISOTOPES
RADIOLOGY
SENSE ORGANS
SYMPTOMS
THERAPY
TRANSITION ELEMENTS
550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)