Rearrangements involving repeated sequences within a P element preferentially occur between units close to the transposon extremities
- Universite Paris, Orsay (France)
In a previous report we described rearrangements occurring at a high rate (30% of the progeny of dysgenic flies) within a cluster of 5S genes internal to a P element. These events were characterized as precise amplifications and deletions of 5S units. Here we analyze recombination events within P elements containing two repeated arrays of 5S genes flanking a central white gene. Deletions (50%) and duplications (3%) of the white gene together with various amounts of flanking 5S genes were observed. These recombinations occur preferentially between the most external 5S units of P transposons. Such rearrangements could be favored by interactions between the proteins bound to the P terminal sequences. 39 refs., 7 figs.
- OSTI ID:
- 543046
- Journal Information:
- Genetics, Vol. 142, Issue 2; Other Information: PBD: Feb 1996
- Country of Publication:
- United States
- Language:
- English
Similar Records
Recombination hot spot in 3.2-kb region of the Charcot-Marie Tooth type 1A repeat sequences: New tools for molecular diagnosis of hereditary neuropathy with liability to pressure palsies and of Charcot-Marie-Tooth type 1A
Transposon-induced promoter scrambling: A mechanism for the evolution of new alleles