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Title: Thermostable cellulase from a thermomonospora gene

Patent ·
OSTI ID:541742

The invention relates to a gene isolated from Thermomonospora fusca, wherein the gene encodes a thermostable cellulase. Disclosed is the nucleotide sequence of the T. fusca gene; and nucleic acid molecules comprising the gene, or a fragment of the gene, that can be used to recombinantly express the cellulase or a catalytically active polypeptide thereof, respectively. The isolated and purified recombinant cellulase or catalytically active polypeptide may be used to hydrolyze substrate either by itself; or in combination with other cellulases, with the resultant combination having unexpected hydrolytic activity. 3 figs.

Research Organization:
Cornell Univ., Ithaca, NY (United States)
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
FG02-84ER13233
Assignee:
Cornell Research Foundation, Inc., Ithaca, NY (United States)
Patent Number(s):
US 5,677,151/A/
Application Number:
PAN: 8-265,429
OSTI ID:
541742
Resource Relation:
Other Information: PBD: 14 Oct 1997
Country of Publication:
United States
Language:
English