PCBs, PCQs and PCDFs in tissues of Yusho and Yu-Cheng patients
All five samples of oil involved in the recent Yu-Cheng outbreak were heavily contaminated with PCBs, PCQs and PCDFs at levels, on the average, of 62, 20 and 0.14 ppm, respectively. The samples not only had roughly one-tenth of the contamination by PCBs, PCQs and PCDFs but also three to four times lower ratios of PCQs and PCDFs to PCBs than samples of oil involved in Yusho in Japan. PCBs, PCQs and PCDFs present were all composed of similar congeners to the ones found in the Yusho specimens, though some variation of the component ratios of PCBs and PCDFs were observed. On the other hand, five patients with Yusho who died 1 to 10 years following poisoning had markedly higher tissue levels of PCDFs and PCQs than did a worker occupationally exposed to PCBs. Taking great differences in the process of the healing and the tissue levels of PCBs, PCQs and PCDFs between the two poisoning cases into consideration, PCDFs and PCQs - especially the former - and not PCBs are deduced to be strongly associated with the development of Yusho.
- Research Organization:
- Osaka Prefectural Institute of Public Health, Japan
- OSTI ID:
- 5414422
- Journal Information:
- Environ. Health Perspect.; (United States), Vol. 59
- Country of Publication:
- United States
- Language:
- English
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Polychlorinated biphenyls, dibenzofurans and quaterphenyls in toxic rice-bran oil and in the blood and tissues of patients with PCB poisoning (Yu-Cheng) in Taiwan
PCB and PCDF congeners in the blood and tissues of Yusho and Yu-Cheng patients
Related Subjects
BENZOFURANS
TISSUE DISTRIBUTION
CHLORINATED AROMATIC HYDROCARBONS
QUATERPHENYLS
VEGETABLE OILS
CHEMICAL ANALYSIS
ADIPOSE TISSUE
BLOOD
JAPAN
LIVER
PATIENTS
TAIWAN
ANIMAL TISSUES
AROMATICS
ASIA
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CONNECTIVE TISSUE
DIGESTIVE SYSTEM
DISTRIBUTION
FURANS
GLANDS
HALOGENATED AROMATIC HYDROCARBONS
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
ISLANDS
MATERIALS
OILS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANS
OTHER ORGANIC COMPOUNDS
TISSUES
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)