Survival of patients with glioblastoma multiforme treated by intraoperative high-activity cobalt 60 endocurietherapy

Journal Article · Sun Oct 01 00:00:00 EDT 1989 · Cancer (Philadelphia); (USA)

DOI:https://doi.org/10.1002/1097-0142(19891001)64:7<1409::AID-CNCR2820640707>3.0.CO;2-R· OSTI ID:5408946

Kumar, P P; Good, R R; Jones, E O; Patil, A A; Leibrock, L G; McComb, R D ^[1]

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1. Univ. of Nebraska College of Medicine, Omaha (USA)

The authors report their initial treatment results in 49 patients with glioblastoma multiforme (GM) who received intraoperative endocurietherapy (ECT) with high-activity cobalt 60 ({sup 60}Co) probe. Thirty poor prognosis (unresectable tumor) patients (Group I) with newly diagnosed GM were treated by either biopsy or subtotal excision, followed by 20.00-Gy single-fraction {sup 60}Co probe ECT, and 60.00-Gy external-beam radiation therapy (EXRT) (80.00 Gy total tumor dose). Nineteen patients (Group II) with recurrent, previously resected and externally irradiated GM were retreated with 20.00-Gy single-fraction {sup 60}Co probe ECT alone. The authors' initial experience with intraoperative ECT of GM is discussed.

• OSTI ID: 5408946
• Journal Information: Cancer (Philadelphia); (USA), Vol. 64:7; ISSN 0008-543X
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
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550603* - Medicine- External Radiation in Therapy- (1980-)