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Title: Influence of radiation therapy on oral Candida albicans colonization: a quantitative assessment

Journal Article · · Oral Surg., Oral Med., Oral Pathol.; (United States)

An increase in quantity of oral Candida albicans was documented in patients receiving head and neck radiation therapy during and after therapy, as assessed by an oral-rinse culturing technique. The amount of the increase was greater in denture wearers and directly related to increasing radiation dose and increasing volume of parotid gland included in the radiation portal. A significant number of patients who did not carry C. albicans prior to radiation therapy developed positive cultures by 1 month after radiation therapy. The percentage of patients receiving head and neck radiation therapy who carried C. albicans prior to radiation therapy did not differ significantly from matched dental patient controls.

Research Organization:
Ohio State Univ., Columbus
OSTI ID:
5407497
Journal Information:
Oral Surg., Oral Med., Oral Pathol.; (United States), Vol. 64:6
Country of Publication:
United States
Language:
English