Information profiles on potential occupational hazards: Chlorophenols. Draft report (Second)
Information profiles are presented on the following compounds: 2-chlorophenol, 3-chlorophenol, 4-chlorophenol, 2,4-dichlorophenol, 2,5-dichlorophenol, 2,6-dichlorophenol, 2,3,6-trichlorophenol, 2,4,5-trichlorophenol, 2,4,6-trichlorophenol. Studies indicate that, administered in acute lethal doses, the chlorophenols produce excitation and increased respiration followed by motor weakness, hypotonia, convulsions, coma, and death. All chlorophenols are well absorbed dermally, and toxic to skin and eyes. Workers exposed to 4-chlorophenol have demonstrated signs of functional disorders of the central and peripheral nervous systems and mucous membrane structure. Testing in mice has produced increased incidences of hepatocellular carcinomas, adenomas, hepatomas, and reticulum cell sarcomas.
- Research Organization:
- Syracuse Research Corp., NY (USA). Center for Chemical Hazard Assessment
- OSTI ID:
- 5400007
- Report Number(s):
- PB-89-216220/XAB; SRC-TR-81-532
- Country of Publication:
- United States
- Language:
- English
Similar Records
Study of the steam distillation of phenolic compounds using ultraviolet spectrometry
Adsorption of chlorophenols on granular activated carbon
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
CHLORINATED AROMATIC HYDROCARBONS
HEALTH HAZARDS
OCCUPATIONAL EXPOSURE
BIOLOGICAL EFFECTS
CHEMICAL PROPERTIES
CONTROL EQUIPMENT
INDUSTRIAL MEDICINE
LETHAL DOSES
OCCUPATIONAL SAFETY
PRODUCTION
TOXIC MATERIALS
TOXICITY
AROMATICS
DOSES
EQUIPMENT
HALOGENATED AROMATIC HYDROCARBONS
HAZARDS
MATERIALS
MEDICINE
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
SAFETY
560300* - Chemicals Metabolism & Toxicology
550900 - Pathology