Microwave-induced temperature, corticosterone, and thryotropin interrelationships

Lu, S T; Lebda, N; Pettit, S; Michaelson, S M

Title: Microwave-induced temperature, corticosterone, and thryotropin interrelationships

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Abstract

To delineate acute endocrine responses to microwave energy absorption, 142 unanesthetized male Long-Evans rats acclimated to experimental procedures were subjected to far-field 2.45-GHz microwave exposure for 1 h at 1-70 mW/cm/sup 2/, 4 h at 0.1-40 mw/cm/sup 2/, or sham exposure. Controls were sham exposed in a sham-exposure chamber beginning at 030 h and killed at 1230, 1330, 1530, and 1930 h. Microwave-exposed rats were equilibrated in an anechoic chamber for 3 h prior to the start of exposure. Microwave exposure was initiated at 1130 h. Exposed rats were killed at 1230 and 1530 h. Colonic temperature (T/sub col/) was measured and serum obtained for thyrotropin (TSH) and corticosterone (CS) determination immediately after exposure. Inverse relations of TSH to power density (PD) or R/sub col/ were noted in the microwave-exposed rats while CS increased with PD or T/sub col/. Similar relations of TSH and CS to T/sub col/ were also noted among ''shams.'' The increase of T/sub col/ by microwave exposure was dependent on PD but independent of an exposure duration greater than 1 h. The serum CS level increasd with PD but the effect decreased with duration of exposure. ''Low intensity'' 4-h microwave exposure inhibited normal circadian elevation ofmore »« less

Authors:: Lu, S T; Lebda, N; Pettit, S; Michaelson, S M

Publication Date:: Thu Jan 01 00:00:00 EST 1981

Research Org.:: Univ. of Rochester, NY

OSTI Identifier:: 5399867

DOE Contract Number:: AC02-76EV03490

Resource Type:: Journal Article

Journal Name:: J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States)

Additional Journal Information:: Journal Volume: 50:2

Country of Publication:: United States

Language:: English

Subject:: 63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; ENDOCRINE GLANDS; SENSITIVITY; MICROWAVE RADIATION; BIOLOGICAL EFFECTS; THERMOREGULATION; CORTICOSTERONE; DAILY VARIATIONS; RATS; TSH; ADRENAL HORMONES; ANIMALS; BODY; CONTROL; CORTICOSTEROIDS; ELECTROMAGNETIC RADIATION; GLANDS; GLUCOCORTICOIDS; HORMONES; HYDROXY COMPOUNDS; KETONES; MAMMALS; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; PITUITARY HORMONES; PREGNANES; RADIATIONS; RODENTS; STEROID HORMONES; STEROIDS; TEMPERATURE CONTROL; VARIATIONS; VERTEBRATES; 560400* - Other Environmental Pollutant Effects; 551000 - Physiological Systems

Citation Formats


                    Lu, S T, Lebda, N, Pettit, S, and Michaelson, S M. Microwave-induced temperature, corticosterone, and thryotropin interrelationships.  United States: N. p., 1981. 
        Web.

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                    Lu, S T, Lebda, N, Pettit, S, & Michaelson, S M. Microwave-induced temperature, corticosterone, and thryotropin interrelationships.  United States.

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                    Lu, S T, Lebda, N, Pettit, S, and Michaelson, S M. 1981.  
        "Microwave-induced temperature, corticosterone, and thryotropin interrelationships".  United States.

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@article{osti_5399867,

  title        = {Microwave-induced temperature, corticosterone, and thryotropin interrelationships},

  author       = {Lu, S T and Lebda, N and Pettit, S and Michaelson, S M},

  abstractNote = {To delineate acute endocrine responses to microwave energy absorption, 142 unanesthetized male Long-Evans rats acclimated to experimental procedures were subjected to far-field 2.45-GHz microwave exposure for 1 h at 1-70 mW/cm/sup 2/, 4 h at 0.1-40 mw/cm/sup 2/, or sham exposure. Controls were sham exposed in a sham-exposure chamber beginning at 030 h and killed at 1230, 1330, 1530, and 1930 h. Microwave-exposed rats were equilibrated in an anechoic chamber for 3 h prior to the start of exposure. Microwave exposure was initiated at 1130 h. Exposed rats were killed at 1230 and 1530 h. Colonic temperature (T/sub col/) was measured and serum obtained for thyrotropin (TSH) and corticosterone (CS) determination immediately after exposure. Inverse relations of TSH to power density (PD) or R/sub col/ were noted in the microwave-exposed rats while CS increased with PD or T/sub col/. Similar relations of TSH and CS to T/sub col/ were also noted among ''shams.'' The increase of T/sub col/ by microwave exposure was dependent on PD but independent of an exposure duration greater than 1 h. The serum CS level increasd with PD but the effect decreased with duration of exposure. ''Low intensity'' 4-h microwave exposure inhibited normal circadian elevation of adrenocortical function in rats if the exposure was coincident with diurnal CS elevation.Inhibition of TSH became more pronounced with duration of exposure. Differences in the endocrine-body temperature relationships between sham- and microwave-exposed rats were also noted. It was concluded that endocrine control was dissociated from body temperature in the microwave-exposed rats. The endocrine control in microwave-exposed rats is different from shams.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/5399867},
  journal      = {J. Appl. Physiol.: Respir., Environ. Exercise Physiol.; (United States)},
number       = ,

  volume       = 50:2,

  place        = {United States},

  year         = {Thu Jan 01 00:00:00 EST 1981},

  month        = {Thu Jan 01 00:00:00 EST 1981}

}

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