Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis

Uri, N; Gips, S; Front, A; Meyer, S W; Hardoff, R

doi:10.1001/archotol.1991.01870180059012

Title: Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis

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Abstract

Qualitative technetium Tc 99m bone scintigraphy using phosphate compounds and gallium 67 scintigraphy were described as a helpful means in diagnosing necrotizing external otitis (NEO). They were, however, claimed to be nonspecific. Quantitative Tc 99m methylene diphosphonate bone scintigraphy and gallium 67 scintigraphy were performed in eight patients with NEO and in 20 patients with severe external otitis, in order to prove usefulness of scintigraphy in the diagnosis of NEO. Ratios of lesion to nonlesion for bone scintigraphy were 1.67 {plus minus} 0.16 in patients with NEO and 1.08 {plus minus} 0.09 in patients with severe external otitis, and for gallium 67 scintigraphy they were 1.35 {plus minus} 0.24 in NEO patients and 1.05 {plus minus} 0.03 in patients with severe external otitis. There was no difference in uptake between diabetic patients with severe external otitis and nondiabetic patients. The scintigraphic studies were also evaluated using a qualitative scoring method (scores 0 to +4), according to the intensity of the radiopharmaceutical uptake. This method was found to be inferior in the diagnosis of NEO compared with the quantitative method. We conclude that lesion-to-nonlesion ratios greater than 1.5 and 1.3 on bone and gallium 67 scintigraphy, respectively, are indicative of NEO.more »« less

Authors:

Uri, N; Gips, S; Front, A; Meyer, S W; Hardoff, R ^[1]

Department of Otolaryngology, Lady Davis Carmel Hospital, Haifa (Israel)

Publication Date:: Sat Jun 01 00:00:00 EDT 1991

OSTI Identifier:: 5397869

Resource Type:: Journal Article

Journal Name:: Archives of Otolaryngology, Head and Neck Surgery; (United States)

Additional Journal Information:: Journal Volume: 117:6; Journal ID: ISSN 0886-4470

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; SENSE ORGANS DISEASES; DIAGNOSIS; SKELETON; SCINTISCANNING; AUDITORY ORGANS; DIABETES MELLITUS; GALLIUM 67; ISOMERIC NUCLEI; NECROSIS; PATIENTS; TECHNETIUM 99; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; ENDOCRINE DISEASES; GALLIUM ISOTOPES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; METABOLIC DISEASES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; PATHOLOGICAL CHANGES; RADIOISOTOPE SCANNING; RADIOISOTOPES; SENSE ORGANS; TECHNETIUM ISOTOPES; YEARS LIVING RADIOI; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

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                    Uri, N, Gips, S, Front, A, Meyer, S W, and Hardoff, R. Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis.  United States: N. p., 1991. 
        Web.  doi:10.1001/archotol.1991.01870180059012.

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                    Uri, N, Gips, S, Front, A, Meyer, S W, & Hardoff, R. Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis.  United States.  https://doi.org/10.1001/archotol.1991.01870180059012

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                    Uri, N, Gips, S, Front, A, Meyer, S W, and Hardoff, R. 1991.  
        "Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis".  United States.  https://doi.org/10.1001/archotol.1991.01870180059012.

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@article{osti_5397869,

  title        = {Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis},

  author       = {Uri, N and Gips, S and Front, A and Meyer, S W and Hardoff, R},

  abstractNote = {Qualitative technetium Tc 99m bone scintigraphy using phosphate compounds and gallium 67 scintigraphy were described as a helpful means in diagnosing necrotizing external otitis (NEO). They were, however, claimed to be nonspecific. Quantitative Tc 99m methylene diphosphonate bone scintigraphy and gallium 67 scintigraphy were performed in eight patients with NEO and in 20 patients with severe external otitis, in order to prove usefulness of scintigraphy in the diagnosis of NEO. Ratios of lesion to nonlesion for bone scintigraphy were 1.67 {plus minus} 0.16 in patients with NEO and 1.08 {plus minus} 0.09 in patients with severe external otitis, and for gallium 67 scintigraphy they were 1.35 {plus minus} 0.24 in NEO patients and 1.05 {plus minus} 0.03 in patients with severe external otitis. There was no difference in uptake between diabetic patients with severe external otitis and nondiabetic patients. The scintigraphic studies were also evaluated using a qualitative scoring method (scores 0 to +4), according to the intensity of the radiopharmaceutical uptake. This method was found to be inferior in the diagnosis of NEO compared with the quantitative method. We conclude that lesion-to-nonlesion ratios greater than 1.5 and 1.3 on bone and gallium 67 scintigraphy, respectively, are indicative of NEO. Quantitative bone scintigraphy, which is quicker to perform, may be used as a single imaging modality for the diagnosis of NEO.},

  doi          = {10.1001/archotol.1991.01870180059012},

  url          = {https://www.osti.gov/biblio/5397869},
  journal      = {Archives of Otolaryngology, Head and Neck Surgery; (United States)},

  issn         = {0886-4470},

  number       = ,

  volume       = 117:6,

  place        = {United States},

  year         = {Sat Jun 01 00:00:00 EDT 1991},

  month        = {Sat Jun 01 00:00:00 EDT 1991}

}

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