HLA-DR typing by radioimmunoassay
Journal Article
·
· Transplantation; (United States)
A radioimmunoassay procedure is described by which peripheral blood lymphocytes can be typed for HLA-DR specificities. The major advantages of this method are the following: simple and reproducible procedure, no need for B lymphocyte separation, no need for optimal viability, and no need for preabsorption of antisera with platelets. This method will find an application in the genetic and biochemical analysis of the HLA complex, and in the clinical tests of Ia antigens for diagnostic or prognostic purposes and in retrospective transplant studies.
- Research Organization:
- Roswell Park Memorial Inst., Buffalo, NY
- OSTI ID:
- 5373455
- Journal Information:
- Transplantation; (United States), Vol. 29:4
- Country of Publication:
- United States
- Language:
- English
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Thu Jan 01 00:00:00 EST 1987
·
OSTI ID:5373455
Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
ANTIGENS
RADIOIMMUNOASSAY
LYMPHOCYTES
IMMUNE REACTIONS
DIAGNOSTIC USES
ANTIGEN-ANTIBODY REACTIONS
BIOCHEMICAL REACTION KINETICS
BLOOD
EVALUATION
IODINE 125
LABELLED COMPOUNDS
PATIENTS
TRANSPLANTS
VIABILITY
ANIMAL CELLS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD CELLS
BODY FLUIDS
CONNECTIVE TISSUE CELLS
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
KINETICS
LEUKOCYTES
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
RADIOASSAY
RADIOISOTOPES
REACTION KINETICS
SOMATIC CELLS
TRACER TECHNIQUES
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551000 - Physiological Systems
550200 - Biochemistry
59 BASIC BIOLOGICAL SCIENCES
ANTIGENS
RADIOIMMUNOASSAY
LYMPHOCYTES
IMMUNE REACTIONS
DIAGNOSTIC USES
ANTIGEN-ANTIBODY REACTIONS
BIOCHEMICAL REACTION KINETICS
BLOOD
EVALUATION
IODINE 125
LABELLED COMPOUNDS
PATIENTS
TRANSPLANTS
VIABILITY
ANIMAL CELLS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD CELLS
BODY FLUIDS
CONNECTIVE TISSUE CELLS
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
KINETICS
LEUKOCYTES
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
RADIOASSAY
RADIOISOTOPES
REACTION KINETICS
SOMATIC CELLS
TRACER TECHNIQUES
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551000 - Physiological Systems
550200 - Biochemistry