The effects of radiation on the thyroid gland: a quantitative analysis

Journal Article · Thu Jan 01 00:00:00 EST 1981 · Prog. Clin. Biol. Res.; (United States)

OSTI ID:5335898

Rall, J E

Radiation can cause cancer of the thyroid, and the thyroid is one of the most radiosensitive tissues. Children are much more sensitive to thyroid irradiation than are adults. The effectiveness of thyroid iodination from radioisotopes of iodine is largely a function of the half-life of the isotope. Short-lived isotopes (/sup 132/I), which give a high dose rate, are essentially equivalent, rad for rad, to x-irradiation. Long-lived isotopes (/sup 131/I) are one-fifth or less as effective as x-ray. Stimulation of the thyroid by TSH markedly increases the carcinogenic potential of thyroid irradiation, and inhibition of TSH stimulation probably decreases the carcinogenic effects of radiation.

• OSTI ID: 5335898
• Journal Information: Prog. Clin. Biol. Res.; (United States), Vol. 74
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
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SIDE EFFECTS
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INTERMEDIATE MASS NUCLEI
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