Radiation-induced recurrent intestinal pseudo-obstruction

Journal Article · Mon Jun 01 00:00:00 EDT 1981 · Am. J. Gastroenterol.; (United States)

OSTI ID:5308254

Conklin, J L; Anuras, S

The syndrome of intestinal pseudo-obstruction is a complex of signs and symptoms of intestinal obstruction without evidence of mechanical obstruction of the intestinal lumen. A patient with radiation-induced intestinal pseudoobstruction is described. The patient is a 74-year old woman with a history of chronic diarrhea, recurrent episodes of crampy abdominal pain, nausea and vomiting since receiving a 13,000 rad radiation dose to the pelvis in 1954. She has been hospitalized on many occasions for symptoms and signs of bowel obstruction. Upper gastrointestinal contrast roentgenograms with small bowel follow-through done during these episodes revealed multiple dilated loops of small bowel with no obstructing lesion. Barium enemas revealed no obstructing lesion. Each episode resolved with conservative therapy. Other secondary causes for intestinal pseudo-obstruction were ruled out in our patient. She gave no history of familial gastrointestinal disorders. Although postirradiation motility abnormalities have been demonstrated experimentally this is the first report of radiation induced intestinal pseudo-obstruction.

• OSTI ID: 5308254
• Journal Information: Am. J. Gastroenterol.; (United States), Vol. 75:6
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
RADIOTHERAPY
SIDE EFFECTS
SMALL INTESTINE
BIOLOGICAL RADIATION EFFECTS
LOCAL IRRADIATION
NAUSEA
PAIN
PATHOLOGY
PATIENTS
RADIATION DOSES
RADIOINDUCTION
VOMITING
BIOLOGICAL EFFECTS
BODY
DIGESTIVE SYSTEM
DOSES
GASTROINTESTINAL TRACT
INTESTINES
IRRADIATION
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
SYMPTOMS
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)
560151 - Radiation Effects on Animals- Man
550901 - Pathology- Tracer Techniques