Cellobiose dehydrogenase from Phanerochaete chrysosporium is encoded by two allelic variants

Journal Article · Sat Feb 01 00:00:00 EST 1997 · Applied and Environmental Microbiology

OSTI ID:530658

Li, Bin; Renganathan, V ^[1]; Nagalla, S R ^[2]

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1. Oregon Graduate Institute of Science and Technology, Portland, OR (United States)
2. Oregon Health Sciences Univ., Portland, OR (United States)

The complete nucleotide sequences of two alleles of cellobiose dehydrogenase, cdh-1 (3,627 bp) and cdh-2 (3,623 bp), from Phanerochaete chrysosporium OGC101 are reported. The nucleotide sequences of cdh-1 and cdh-2 exhibit 97% similarity. A total of eighty-six point mutations between cdh-1 and cdh-2 are observed. Both alleles have 14 exons, and the introns are located at exactly the same positions. The translation products of these alleles have identical amino acid sequences. Restriction fragment length polymorphism analyses of homokaryotic derivatives show segregation of the CDH alleles. 22 refs., 4 figs.

• DOE Contract Number: FG06-92ER20065
• OSTI ID: 530658
• Journal Information: Applied and Environmental Microbiology, Vol. 63, Issue 2; Other Information: PBD: Feb 1997
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
PHANEROCHAETE
MUTATIONS
CELLOBIOSE
GENETIC CONTROL