Limitations of quantitative phase analysis for detection of coronary artery disease in patients with impaired LV-function
Phase analysis of radionuclide ventriculograms is used for identifying ischemic wall motion abnormalities. Myocardial segments with an abnormal phase and the synchronicity of LV wall motion can be assessed from a histogram of LV phase distribution. We examined in this study the sensitivity of SDP-LV for identifying coronary artery disease and its specificity in patients with normal and various degrees of left ventricular impairment. A total of 84 patients were studied. In severe left ventricular impairment, phase analysis did not aid in distinguishing coronary artery disease from other causes of ventricular dysfunction. By contrast, phase analysis was highly sensitive and specific for coronary artery disease in patients with normal or moderately depressed left ventricular function.
- Research Organization:
- California Univ., Los Angeles (USA)
- DOE Contract Number:
- AC03-76SF00012
- OSTI ID:
- 5301788
- Report Number(s):
- DOE/SF/00012-T24; ON: DE84007322
- Resource Relation:
- Other Information: Portions are illegible in microfiche products
- Country of Publication:
- United States
- Language:
- English
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