Diuretic radionuclide renography and scintigraphy in the differential diagnosis of hydroureteronephrosis

Journal Article · Wed Apr 01 00:00:00 EST 1981 · Semin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1016/S0001-2998(81)80040-2· OSTI ID:5284198

Thrall, J H; Koff, S A; Keyes, Jr, J W

Conventional radionuclide renography has been modified to include a pharmacologic intervention by administration of intravenous furosemide. The procedure is applied in patients with hydroureteronephrosis to distinguish dilated, nonobstructed systems from those with significant mechanical obstruction. Diagnostic patterns are derived from computer-generated time-activity histograms that depict the accumulation of radiotracer prior to diuresis and in response to diuresis. In dilated, nonobstructed systems, increased urine flow following diuresis causes a decline or washout of activity. In significantly obstructed systems, there is a failure of tracer activity to decrease in response to diuresis. The procedure is applied most commonly in suspected ureteropelvic junction and ureterovesical junction obstruction. The significance of residual urinary tract dilatation following corrective surgery also can be readily assessed. The major current limitation to the technique is poor renal function with inadequate response of urine flow to diuresis.

• OSTI ID: 5284198
• Journal Information: Semin. Nucl. Med.; (United States), Vol. 11:2
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
KIDNEYS
RENOGRAPHY
LABELLED COMPOUNDS
DIAGNOSTIC USES
URINARY TRACT
UROGENITAL SYSTEM DISEASES
DIAGNOSIS
AGE GROUPS
COMPARATIVE EVALUATIONS
PATIENTS
SURGERY
TRACER TECHNIQUES
BIOMEDICAL RADIOGRAPHY
BODY
DIAGNOSTIC TECHNIQUES
DISEASES
ISOTOPE APPLICATIONS
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIOLOGY
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques
550901 - Pathology- Tracer Techniques