Effects of fiber type and diet on nuclear magnetic resonance (NMR) relaxation times of skeletal muscle

Conference · Sat Mar 01 00:00:00 EST 1986 · Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)

OSTI ID:5277695

Mardini, I A; McCarter, R J; Fullerton, G D

NMR studies of muscle have typically used muscles of mixed fiber composition and have not taken into account the metabolic state of the host. Samples of psoas (type IIB fibers) and soleus (type I fibers) muscles were obtained from 3 groups of rabbits: group C, fed regular chow; group DK fed a potassium deficient diet; and group HC fed a high cholesterol diet. The T/sub 1/ and T/sub 2/ relaxation times of psoas and soleus muscles were not significantly different for group C. Following dietary manipulation, (groups KD and HC), however, the relaxation times of the psoas and soleus muscles were significantly different. There was also a significant difference in water content of psoas muscles in groups KD and HC vs. group C but the observed differences in NMR results could be only partially accounted for by the shift in water content. The authors results suggest that (1) changes in ion or cholesterol concentration are capable of inducing changes in water bonding and structuring in muscle tissues; (2) diet must be added to the growing list of environmental factors that can cause NMR contrast changes; (3) selective use of muscles rich in one fiber type or another for NMR measurements could provide either control or diagnostic information, related to changes in body composition.

• Research Organization: Univ. of Texas Health Science Center, San Antonio
• OSTI ID: 5277695
• Report Number(s): CONF-8604222-
• Journal Information: Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States), Vol. 45:3; Conference: 70. annual meeting of the Federation of American Society for Experimental Biology, St. Louis, MO, USA, 13 Apr 1986
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
MUSCLES
CHEMICAL COMPOSITION
NMR SPECTRA
CHOLESTEROL
DIET
FIBERS
NUCLEAR MAGNETIC RESONANCE
POTASSIUM
RABBITS
ALKALI METALS
ANIMALS
ELEMENTS
HYDROXY COMPOUNDS
MAGNETIC RESONANCE
MAMMALS
METALS
ORGANIC COMPOUNDS
RESONANCE
SPECTRA
STEROIDS
STEROLS
VERTEBRATES
550600* - Medicine