Influence of cadmium on caries and the cariostatic properties of fluoride in rats

Journal Article · Thu May 01 00:00:00 EDT 1980 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1980.10667488· OSTI ID:5274599

Shearer, T R; Britton, J L; DeSart, D J; Johnson, J R

Cadmium injections during molar tooth development in the rat were strongly caries-promoting in female rats. Cadmium also partially negated the cariostatic effect of fluoridated drinking water in both male and female rats. The mechanism for the caris-promoting propeties of cadmium is unknown, but may be related to cadmium uptake into enamel and dentin. Cadmium was taken up into molar enamel and dentin in proportion to the amount of cadmium administered, but cadmium did not influence uptake of fluoride onto erupted enamel. Calcium and ash concentrations in molar enamel were not altered by cadmium administration.

• Research Organization: Univ. of Oregon Health Sciences Center, Portland
• OSTI ID: 5274599
• Journal Information: Arch. Environ. Health; (United States), Vol. 35:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CADMIUM
BIOLOGICAL EFFECTS
RATS
METABOLISM
BIOCHEMICAL REACTION KINETICS
CALCIUM
CARIES
DENTIN
DRINKING WATER
EXPERIMENTAL DATA
FEMALES
FLUORINATION
MALES
TABLES
TEETH
UPTAKE
ALKALINE EARTH METALS
ANIMALS
CHEMICAL REACTIONS
DATA
DATA FORMS
DIGESTIVE SYSTEM
DISEASES
ELEMENTS
HALOGENATION
HYDROGEN COMPOUNDS
INFORMATION
KINETICS
MAMMALS
METALS
NUMERICAL DATA
ORAL CAVITY
OXYGEN COMPOUNDS
PATHOLOGICAL CHANGES
REACTION KINETICS
RODENTS
VERTEBRATES
WATER
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)