Membrane interfaces for sample introduction in capillary zone electrophoresis

Journal Article · Fri May 01 00:00:00 EDT 1992 · Analytical Chemistry (Washington)

DOI:https://doi.org/10.1021/ac00033a006· OSTI ID:526059

Bao, L; Dasgupta, P K ^[1]

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1. Texas Tech Univ., Lubbock, TX (United States)

Small lengths of narrow-bore tubular membranes can be interposed in the separation capillary in capillary electrophoretic separation systems. These membrane segments can be used as sampling interfaces; a jacket is built outside the membrane, and the sample is introduced by diffusion/permeation through the membrane. Various examples are shown; the determination of gaseous samples through a porous membrane, the determination of ionizable/nonionic solutes by permeation through a silicone rubber membrane, and the separation of low MW constituents in blood plasma by transport through a dialysis membrane. In the first two cases, significant preconcentration is possible, thus permitting attractive detection limits. 23 refs., 10 figs., 2 tabs.

• Sponsoring Organization: USDOE
• DOE Contract Number: FG05-84ER13281
• OSTI ID: 526059
• Journal Information: Analytical Chemistry (Washington), Vol. 64, Issue 9; Other Information: PBD: 1 May 1992
• Country of Publication: United States
• Language: English

Related Subjects

44 INSTRUMENTATION
INCLUDING NUCLEAR AND PARTICLE DETECTORS
54 ENVIRONMENTAL SCIENCES
55 BIOLOGY AND MEDICINE
BASIC STUDIES
DETECTION
LIMITING VALUES
MEMBRANES
INTERFACES
PERMEABILITY
POROSITY
SEPARATION EQUIPMENT
PERFORMANCE
EFFICIENCY
USES
DIALYSIS
DIFFUSION
ELECTROPHORESIS
MASS TRANSFER
CAPILLARY FLOW
CAPILLARIES
LIQUID COLUMN CHROMATOGRAPHY
SAMPLE PREPARATION
FILTERS