Chronic manganese intoxication

Journal Article · Sun Oct 01 00:00:00 EDT 1989 · Archives of Neurology; (USA)

DOI:https://doi.org/10.1001/archneur.1989.00520460090018· OSTI ID:5257147

Huang, C C; Chu, N S; Lu, C S; Wang, J D; Tsai, J L; Tzeng, J L; Wolters, E C; Calne, D B ^[1]

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1. Chang Gung Medical College Hospital, Taipei, Taiwan (China)

We report six cases of chronic manganese intoxication in workers at a ferromanganese factory in Taiwan. Diagnosis was confirmed by assessing increased manganese concentrations in the blood, scalp, and pubic hair. In addition, increased manganese levels in the environmental air were established. The patients showed a bradykinetic-rigid syndrome indistinguishable from Parkinson's disease that responded to treatment with levodopa.

• OSTI ID: 5257147
• Journal Information: Archives of Neurology; (USA), Vol. 46:10; ISSN 0003-9942
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
MANGANESE
TOXICITY
NERVOUS SYSTEM DISEASES
EPIDEMIOLOGY
BIOLOGICAL ACCUMULATION
BLOOD
CHRONIC EXPOSURE
HAIR
METABOLISM
METALLURGY
OCCUPATIONAL DISEASES
OCCUPATIONAL EXPOSURE
PERSONNEL
TAIWAN
ASIA
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
DISEASES
ELEMENTS
ISLANDS
MATERIALS
METALS
ORGANS
SKIN
TRANSITION ELEMENTS
560300* - Chemicals Metabolism & Toxicology