Evaluation of radioactive phosphorus in the palliation of metastatic bone lesions from carcinoma of the breast and prostate

Journal Article · Tue Jan 01 00:00:00 EST 1980 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.134.1.6153129· OSTI ID:5246462

Cheung, A ^[1]; Driedger, A A

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1. Univ. of Western Ontario, London, Canada

Radioactive phosphorus effected substantial palliation of intractable bone pain in 17 of 33 (51.5%) women with metastatic carcinoma of the breast and in 14 of 15 (93.3%) men with metastatic carcinoma of the prostate. No significant difference in the overall response rate was found between androgen and paralthormone priming prior to radiophosphorus therapy. The degree of response was not dependent on total dose of /sup 32/P within the range of 9 to 18 mCi (333 to 666 MPq). Myelosuppression was a transient complication in 9 of 33 patients with metastatic breast carcinoma and in 7 of 15 patients with metastatic prostate carcinoma. Symptomatic hypercalcemia was an infrequent complication of radiophosphorus therapy irrespective of the priming regimen.

• OSTI ID: 5246462
• Journal Information: Radiology; (United States), Vol. 134:1
• Country of Publication: United States
• Language: English

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