Methylation gives mom/dad distinction
Journal Article
·
· BioScience; (United States)
OSTI ID:5243452
Among mammals, genes inherited from the mother and father are often not interchangeable. Experiments on mice have demonstrated that certain genes of maternal origin are required for the development of a fetus, while specific paternal genes are necessary for the placenta and other extraembryonic tissues. How is the maternal or paternal origin marked onto a gene before fertilization. One hypothesis has been that simple chemical groups, called methyl groups, are added or removed from the chromosomes during the production of gametes. Now two research groups, using recombinant DNA methods, have obtained evidence supporting that hypothesis.
- OSTI ID:
- 5243452
- Journal Information:
- BioScience; (United States), Vol. 37:9
- Country of Publication:
- United States
- Language:
- English
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