CT appearance of acute radiation-induced injury in the lung
To determine how soon radiation-induced lung injury is detectable, to compare the CT findings with those on chest radiographs, and to observe the appearance of the abnormality during the acute phase, we performed 83 CT studies in 17 radiotherapy patients at relatively short intervals. All 17 patients received fractionated radiotherapy to the thorax with a large irradiated lung volume. The CT findings were variable; pulmonary infiltrates were homogeneous, patchy, or discrete. CT abnormalities were evident in 15 of 17 cases within 16 weeks after radiotherapy; in 13 of these it was detected within 4 weeks. In three of these 15 cases, no abnormality was detected on chest radiographs, and in three other cases, the change was observed much later on chest radiographs than on CT scans. In the other nine cases, abnormalities were detected simultaneously on CT scans and chest radiographs. In four cases, extensive radiation pneumonitis was observed on CT, but in two of these, the change was misdiagnosed on the chest radiograph. We conclude that CT is useful in the detection of acute radiation-induced pulmonary disease.
- Research Organization:
- Osaka Univ. Medical School (Japan)
- OSTI ID:
- 5233239
- Journal Information:
- AJR, Am. J. Roentgenol.; (United States), Vol. 150:4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
LUNGS
BIOLOGICAL RADIATION EFFECTS
PNEUMONIA
RADIOINDUCTION
RADIOTHERAPY
SIDE EFFECTS
BIOMEDICAL RADIOGRAPHY
CHEST
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DOXORUBICIN
PATIENTS
RADIATION INJURIES
ANTI-INFECTIVE AGENTS
ANTIBIOTICS
ANTINEOPLASTIC DRUGS
BIOLOGICAL EFFECTS
BODY
BODY AREAS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
INJURIES
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
THERAPY
TOMOGRAPHY
560151* - Radiation Effects on Animals- Man
550602 - Medicine- External Radiation in Diagnostics- (1980-)